Human blood T lymphocytes that suppress the mixed leukocyte culture reactivity of lymphocytes from HLA-B14 bearing individuals
Bean, M.A.; Akiyama, M.; Kodera, Y.; Dupont, B.; Hansen, J.A.
Journal of Immunology 123(4): 1610-1614
1979
ISSN/ISBN: 0022-1767 PMID: 90092 Document Number: 142705
A nontransfused male patient with recurrent bladder carcinomata has been demonstrated to have blood T lymphocytes that suppress the MLC responsiveness of lymphocytes only from normal individuals positive for HLA-B14. Unexpectedly, this T-suppressor cell differs from three other reported blood T-suppressor cells arising in man in that it apparently does not require HLA-D locus compatibility between the suppressor cell and the lymphocyte being suppressed.
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