Calcium-loading test and bone disease in patients with urolithiasis
Lindergård, B.; Colleen, S.; Månsson, W.; Rademark, C.; Rogland, B.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 20: 460-465
1983
ISSN/ISBN: 0071-2736 PMID: 6657669 Document Number: 214690
A group of 121 patients with a history of multiple or complicated calcium urolithiasis were divided into three subgroups: normal, absorptive and renal/resorptive calciuria by means of a calcium-loading test. Patients with renal hypercalciuria had lower bone mineral content (BMC) than the other groups but did not differ in amount of bone or TmPO4/GFR. The 24-hour urine calcium excretion was elevated in patients with renal and absorptive type of hypercalciuria but not in patients with normal calcium-loading test and there was no correlation to BMC. The c-AMP/creatinine seemed to discriminate patients with resorptive calciuria from patients with renal calciuria. It is suggested that only patients with renal hypercalciuria should be treated with calcium-retaining drugs such as thiazides.