Penetration of chromate ions in damaged and undamaged skin of sensitized and nonsensitized individuals occupationally exposed to chromates
Tronnier, H.; Kühl, M.; Lehmann, E.; Träbing, H.; Wölcke, U.
Dermatosen in Beruf und Umwelt. Occupation and Environment 31(1): 19-23
1983
ISSN/ISBN: 0343-2432 PMID: 6220882 Document Number: 214254
The importance of oversensitivity to chromate within the framework of occupational dermatoses is sufficiently well known. Questions still remained unanswered as to which substances and solutions in which form and quantity sensitivity to chromate occurs. Further, it is unclear why one worker reacts allergically and another remains unaffected carrying out the same work. In spite of all attempts it is as a rule still impossible to predict who will be affected. By investigating the penetration of chromate ions, we wanted to draw attention to possible dangers those beginning work are exposed to. We are aware that a complex series of questions exists but that only a small part can be approached at once. It appeared appropriate to determine whether the level of penetration of the metal ions differs between individuals, in particular whether the rate is higher in sensitive than in non-sensitive people. To handle this question a method had to be found to determine metal ions with and without exposure in the skin.