Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat
Kanai, S.; Kitani, K.
Research Communications in Chemical Pathology and Pharmacology 42(3): 423-430
1983
ISSN/ISBN: 0034-5164 PMID: 6665300 Document Number: 213974
A combined infusion of taurocholate (TC) and glycoursodeoxycholate (GU) resulted in a longer choleretic period and a significantly higher excretion of TC compared with the infusion of TC alone, as has been previously observed for the combined infusion of tauroursodeoxycholate (TU) and TC in the rat. It was concluded that GU is as effective as TU in preventing TC induced cholestasis in this species.