Periodic effects of 5 g acceleration on the kinetics of erythrocyte hemolysis in white rats
Agamalyan, A.G.; Oganesyan, S.S.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 17(6): 60-62
1983
ISSN/ISBN: 0321-5040 PMID: 6656190 Document Number: 212126
The effect of daily acceleration of 5 g applied for 25 min on the kinetic parameters of erythrocyte hemolysis was studied on 30 white Wistar rats. The animals were accelerated in a centrifuge with a 3.25 m rotor for 2 wk. Hemolysis was recorded in a modified device that permitted phase analysis of the resultant curves. The selected kinetic parameters varied in a different degree and recovered during readaptation in a nonuniform manner. This is associated with various changes in different components of the regulation of erythrocyte hemolytic resistance. [Applications to aerospace physiology are suggested.].