Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of maternal hypervitaminosis A during late gestation on pre- & postnatal lung maturation in rat

Singh, S.; Padmanabhan, R.; Singh, G.; Kaur, G.

Indian Journal of Experimental Biology 21(3): 103-107

1983

ISSN/ISBN: 0019-5189
PMID: 6654391
Document Number: 210721
On days 16 to 18 or 17 to 19 of pregnancy CF rats were given 15 000 or 20 000 IU vitamin A by mouth. Mean volume and weight of amniotic fluid were significantly greater for foetuses of rats given vitamin A than for those of controls. Histological study showed that lungs of foetuses of rats given vitamin A had differentiation delayed by 2 days. When treated rats were allowed to proceed to delivery, their offspring showed higher perinatal mortality, smaller litter size and lower birthweight that those of controls; sucking was delayed and they showed respiratory distress. Lungs of offspring 1 to 7 days old showed poor differentiation of pulmonary tissue, thick septae, near absence of secondary septae and delayed vascularization.

Document emailed within 1 workday
Secure & encrypted payments

Campos, G.A.; Guerra, F.A.; Brümmer, E.; Muñoz, M.L.; Vega, I.A. 1992: Synergistic effect of cortisol and thyrotrophin releasing hormone on lung maturation in the fetal sheep entails connective tissue maturation Biological Research 25(2): 95-100
Kumar, S.; Das, J.K.; Pandey, S.K. 2005: Neuroembryotoxic effect of 5- Fluorouracil in rat: injecting in late phase of gestation Nepal Medical College Journal: Nmcj 7(2): 83-86
Baksi, S.N. 1978: Effect of maternal thyroparathyroidectomy during gestation on feto-placental development in rats Indian Journal of Experimental Biology 16(12): 1281-1283
Pehrson, B.; Hakkarainen, J.; Blomgren, L. 1990: Vitamin E status in newborn lambs with special reference to the effect of dl-alpha-tocopheryl acetate supplementation in late gestation Acta Veterinaria Scandinavica 31(3): 359-367
Barry, D.; Frew, A.Hailemichael.; Mohammed, H.; Desta, B.Fekadu.; Tadesse, L.; Aklilu, Y.; Biadgo, A.; Buffington, S.Tebben.; Sibley, L.M. 2014: The effect of community maternal and newborn health family meetings on type of birth attendant and completeness of maternal and newborn care received during birth and the early postnatal period in rural Ethiopia Journal of Midwifery and Women's Health 59 Suppl. 1: S44-S54
Webster, E.H.; Hilfer, S.R.; Searls, R.L.; Kornilow, J. 1993: Effect of tunicamycin on maturation of fetal mouse lung American Journal of Physiology 265(3 Pt 1): L250-L259
Padmanabhan, R.; Singh, G.; Singh, S. 1981: Malformations of genitourinary system resulting from maternal hypervitaminosis a in rat Indian Journal of Experimental Biology 19(1): 32-36
Burov, I.V.; Ostrovskaia, R.U.; Smol'nikova, N.M.; Trofimov, S.S.; Savchenko, N.M. 1987: Normalizing effect of GABA derivatives on late behavioral disorders occurring in rats with early postnatal suppression of protein synthesis Farmakologiia i Toksikologiia 50(4): 18-22
Tömböl, T. 1980: Some data on postnatal maturation of the cerebral cortex in cat Acta Biologica Academiae Scientiarum Hungaricae 31(1-3): 341-365
Sundari, S.Bala.Tripura.; Venu, L.; Sunita, Y.; Raghunath, M. 2007: Chronic maternal dietary iodine deficiency but not thiocyanate feeding affects maternal reproduction and postnatal performance of the rat Indian Journal of Experimental Biology 45(7): 603-609
Bamford, O.S.; Sterni, L.M.; Wasicko, M.J.; Montrose, M.H.; Carroll, J.L. 1999: Postnatal maturation of carotid body and type I cell chemoreception in the rat American Journal of Physiology 276(5): L875-L884
Hannecke, V.; Mayoux-Benhamou, M.A.; Michel, P.; Pompidou, A.; Barbet, J.P. 2001: Fetal development and postnatal maturation of the longus colli muscle Morphologie: Bulletin de l'Association des Anatomistes 85(269): 13-17
Lee, J.N.; Grudzinskas, J.G.; Chard, T. 1981: Effect of smoking on maternal blood SP1 levels in late pregnancy Obstetrics and Gynecology 57(2): 220-223
Cuenca Navarro, N.; de Juan Herrero, J.; Fernández Jover, E. 1989: Stages in the postnatal maturation of the optic nerve: morphometric changes during the critical period Archivos de Neurobiologia 52(1): 1-8
Garel, J.M.; Pic, P. 1972: Evolution of phosphatemia in the rat fetus during the late stages of gestation Biology of the Neonate 21(5): 369-374
Zink, M.C.; Johnson, J.A. 1984: Cellular constituents of clinically normal foal bronchoalveolar lavage fluid during postnatal maturation American Journal of Veterinary Research 45(5): 893-897
Yaginuma, T. 1981: Possible circadian periodicity of foetal prolactin secretion late in gestation Acta Endocrinologica 98(1): 106-111
Dharmarajan, A.M.; Bruce, N.W.; Meyer, G.T. 1989: Quantitative comparison of luteal histology in the rat and rabbit: changes from mid- to late gestation Journal of Anatomy 166: 191-201
Kasius, R.V.; Randall, A.; Tompkins, W.T.; Wiehl, D.G. 1958: Maternal and newborn nutrition studies at Philadelphia Lying-In Hospital; newborn studies. VI. Infant size at birth and parity, length of gestation, maternal age, height, and weight status Milbank Memorial Fund Quarterly 36(4): 335-362
Braaksma, M.A.; Dassel, A.C.; Aarnoudse, J.G. 1999: Renal responses to prolonged (48 h) hypoxemia without acidemia in the late-gestation ovine fetus American Journal of Physiology 277(2): R395-R402