Immunomicrobiological monitoring of orovaccinal therapy in acute intestinal infections
Corridori, S.; Negretti, F.
Developments in Biological Standardization 53: 285-297
1983
ISSN/ISBN: 0301-5149 PMID: 6873470 Document Number: 202350
A double blind study in 42 patients (treated and controls) affected by acute uncomplicated salmonellosis was performed. The treatment consisted of an oral inactivated tetravaccine at the dose of 1 ampoule twice a day for 15 consecutive days. Microbiological and serological techniques (determination of intestinal secretory IgA by means of immunofluorescence, titration of copro and serum antibodies, quali-quantitative coprocultures) have shown that the administration of oral vaccine improved both the clinical and the immunomicrobiological picture in treated patients.