UDP-coenzymes in glioma tissue of human brain

Popova, G.M.

Voprosy Meditsinskoi Khimii 29(1): 20-23

1983


ISSN/ISBN: 0042-8809
PMID: 6836953
Document Number: 202010
UDP-coenzymes (UDP glucose (UDPG), UDP-N-acetylglucosamne (UDPAG), UDPG/UDPAG and UDPAG/UDPG ratios) were studied in rabbit and human brain tissues, and in the tissue of human glial brain tumors of varying dedifferentiation. Data were presented on UDP-coenzymes in oligodendrogliomas, astrocytomas and in dedifferentiating astrocytomas and glioblastomas. The UDPAG/UDPG ratio increased with tumor dedifferentiation. An increase in UDPAG level may be to a certain extent linked with an increased level of protein-bound mucolipids in glial tumors.

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