Post-mortem observation of glioma and/or brain tissue compared to C-T scan findings after irradiation
Nakamura, N.; Kojima, H.; Nagashima, K.; Aida, T.; Kaneko, S.; Kitaoka, K.; Abe, H.
Gan no Rinsho. Japan Journal of Cancer Clinics 35(11): 1313-1323
1989
ISSN/ISBN: 0021-4949 PMID: 2810775 Document Number: 346209
C-T scan findings in glioma and brain tissue after irradiation were histopathologically analyzed with the post-mortem examination of 4 patients. High density of contrast enhancement observed in gliomas mainly corresponded to proliferation of irregular blood vessels and hypodensity reflected less cellular area or necrotic foci in the tumor tissue. A mottled lesion with high density margin in C-T of radionecrosis of the brain tissue observed in a non-glioma patient was formed by coagulation necrosis showing marked proliferation of telangiectatic blood vessels in periphery of lesion and acellular area in the center. It is occasionally impossible to differentiate the findings between delayed radionecrosis of brain and recurrence of glioma using the C-T criteria alone.