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Infantile renal tumors associated with hypercalcemia. Characterization of intermediate-filament clusters

Rousseau-Merck, M.F.; Nogues, C.; Nezelof, C.; Marin-Cudraz, B.; Paulin, D.

Archives of Pathology and Laboratory Medicine 107(6): 311-314

1983

ISSN/ISBN: 0003-9985
PMID: 6342566
Document Number: 197312
Three cases of hypercalcemic infantile renal tumors were studied to identify the proteins related to their cytoplasmic 8- to 10-nm filament clusters. Immunofluorescence microscopy, using antibodies against vimentin, cytokeratin, and actin, led to the characterization of vimentin-positive filament clusters. We discuss the possibility of a mesenchymal origin for these tumors.

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