Hypercalcemia associated with tumors in children. 20 cases
Leblanc, A.; Hartmann, O.; Pons, G.; Caillaud, J.M.; Couanet, D.; Lenoir, G.; Lemerle, J.
Archives Francaises de Pediatrie 41(8): 551-555
1984
ISSN/ISBN: 0003-9764 PMID: 6508484 Document Number: 226642
Thirty episodes of hypercalcemia were observed in 20 children with solid tumors: principally 9 cases of non Hodgkin's lymphomas, 4 cases of rhabdomyosarcomas and 4 cases of Wilms' tumors. The 2 children with neurological manifestations and hypertension had the most severe symptoms secondary to the high calcium levels. However, hypercalcemia was asymptomatic in 8 of the 20 children. Focal seizures and metastatic calcifications subsequently occurred in 6 children. Emergency treatment of hypercalcemia often had partial or transient efficiency. In contrast, high calcium levels always returned to normal after anti-tumoral treatment.