Mechanism of DNA-histone crosslinks in UV-irradiated nuclei
Saito, I.; Sugiyama, H.; Matsuura, T.
Nucleic Acids Symposium Series 11: 225-228
1982
ISSN/ISBN: 0261-3166 PMID: 7183962 Document Number: 196735
Mechanism of the DNA-histone crosslinks in UV-irradiated chicken erythrocyte nuclei has been investigated. It has been demonstrated that the major chemical reaction induced by irradiation of DNA-histone complexes is the crosslinking between lysine and thymine residues and subsequent transfer of thyminyl group from DNA to lysine residues of histones.
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