Use of transferrin as a gene-carrier to the erythroid cells of the marrow
Stavridis, J.C.; Psallidopoulos, M.
Cellular and Molecular Biology 28(1): 15-18
1982
ISSN/ISBN: 0145-5680 PMID: 7044549 Document Number: 196037
The ability of transferrin to enter red cell precursors by endocytosis was employed in order to insert genetic material into canine erythroblasts in vivo. This was facilitated with the formation of a DNA-histone-transferrin complex in vitro. A large amount of genetic material was successfully inserted into cells.
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