Screening, detection and biotransformation of lormetazepam, a new hypnotic agent from the 1,4-benzodiazepine series
Schütz, H.; Fitz, H.
Arzneimittel-Forschung 32(3): 177-183
1982
ISSN/ISBN: 0004-4172 PMID: 6123328 Document Number: 196028
The paper describes a screening procedure for 7-chloro-5-(2-chlorphenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin- 2-one (lormetazepam, Noctamid) and other important analytical data (TLC, GLC, UV-, IR- and mass spectra) of this new benzodiazepine derivative. Screening results after a single p.o. dose of 1 mg lormetazepam (Noctamid-1) are also reported.
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