Preliminary report on the stimulation of immunity to the larval stage of Taenia multiceps
Verster, A.; Tustin, R.C.
Journal of the South African Veterinary Association 53(3): 175-176
1982
ISSN/ISBN: 1019-9128 PMID: 7175904 Document Number: 195530
The efficacy of Oncosphere Secretory Antigen (OSA) in protecting sheep against the larval stage of Taenia multiceps was assessed in 47 sheep in 2 trials. In the pilot trial no cerebral coenuri were found in 3 sheep which were treated with OSA 28 and 14 days before challenge with 6 000 eggs of T. multiceps. Cerebral coenuri were present in 3 untreated controls. In the second experiment 30 sheep were similarly treated with OSA and challenged with 5 000 eggs of T. multiceps, while 11 sheep served as untreated controls. At necropsy either developing coenuri or degenerate lesions were present in the brain of 5 (16,6%) of the 30 vaccinated animals while 8 out of 11 (72,7%) of the untreated animals had cerebral coenuri or degenerate lesions in the brain. It is concluded that OSA may be used to protect animals against cerebral coenuriosis.