Electron microscopic detections on emulsions of perfluorocarbon blood substitute
Dai, Z.Q.
Zhongguo Yao Li Xue Bao 3(1): 35-37
1982
ISSN/ISBN: 0253-9756 PMID: 6211901 Document Number: 194683
An improved EM method of negative staining is presented for determining the emulsion droplets of perfluorocarbon artificial blood. The resolving power is 0.01 .mu.m. Both emulsions I and II consisted of ultrafine droplets of O/W [oil/H2O] type. The average diameters of droplet (.gtoreq. 0.04 .mu.m) were 0.08 and 0.09 .mu.m, respectively. The maximum diameter for all droplet distributions were below 0.02 .mu.m. It seems that the droplet size target of the emulsions has caught up with more advanced levels. Emulsion I was more stable than II, which contained 0.2% droplets of .gtoreq. 0.4 .mu.m and caused little toxicity to macrodroplets.