The regional differences of catecholaminergic neuron systems in experimental hydrocephalus of rabbits (authors transl)
Miwa, S.
Nihon Geka Hokan. Archiv für Japanische Chirurgie 51(1): 70-78
1982
ISSN/ISBN: 0003-9152 PMID: 7092467 Document Number: 193800
Contents of noradrenaline (NA), dopamine (DA) and their metabolites were determined in 7 brain regions of rabbits with kaolin-induced hydrocephalus (2 days, 1 wk and 4 wk after intracisternal kaolin injection). NA contents decreased 2 days after kaolin injection in cerebellum, hypothalamus and pons + medulla. DA contents were unchanged in all brain regions. Contents of 3-methoxy-4-hydroxyphenylethaleneglycol sulfate, the major NA metabolite, were elevated in all brain regions through the courge of hydrocephalus formation. Contents of homovanillic acid, the major DA metabolite, decreased in cerebral cortex and caudate nucleus, but increased in cerebellum, hypothalamus, midbrain and pons + medulla.