Clinical use of amoxicillin in the otorhinolaryngological field (authors's transl)
Maeda, T.
Japanese Journal of Antibiotics 29(4): 385-390
1976
ISSN/ISBN: 0368-2781 PMID: 933332 Document Number: 96951
Forty-eight cases of otorhinolaryngological infections were treated with amoxicillin (AMPC) at a daily dose of 750mg. The clinical and microbiological effects were studied, and the results were summarized as follows. 1. The subjects comprised 20 cases of otitis media, 10 of tonsillitis, 4 of sinusitis, 4 of chroditis, 2 bronchitis, 5 of furuncle of the ear and 3 of furuncle of the nose. The clinical effective rate of AMPC was 82.9%, and the microbiological effective rate was 80.6%. 2. The effect of AMPC against strains isolated from the above diseases was also studied. The effective rate against Streptococcus was 91.6% and against Staphylococcus 83.3%. 3. Side effects were observed in 4 cases (one of diarrhea, two of abdominal discomfort and one of lingual pain), but none of them was so severe as the use of AMPC should have been discontinued.