Biological properties of Trimeresurus mucrosquamatus venom and its fractions
Lu, C.H.; Chou, F.Y.; Tsai, M.Y.
Zhonghua Minguo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 15(2): 113-118
1982
ISSN/ISBN: 0253-2662 PMID: 7094682 Document Number: 192240
T. mucrosquamatus venom was separated into 2 principle fractions by Sephadex G-100 gel filtration. Fraction 1 (FI) contained the main part of lethal and hemorrhagic activities [in mice and rabbits, respectively] and minor part of proteolytic activity on casein. The LD of FI determined by i.v. injection of mice was significantly smaller than that of i.p. injection, while the results with fraction 2 (FII) were reversed. The venom was susceptible to heat, pH and Cys-HCl, but not to albumin, sodium glutamate, sorbitol and glycine.