Titers of antibodies against antigen O of E. coli O14 in patients with inflammatory diseases of the large intestine
Shadrin, B.P.; Khalif, I.L.; Turovtseva, V.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 8: 63-65
1982
ISSN/ISBN: 0372-9311 PMID: 6184915 Document Number: 191052
The content of serum antibodies to E. coli O14 O-antigen in patients with inflammatory diseases of the large intestine was studied in the passive hemagglutination test. These antibodies were detected in 77% of patients with nonspecific ulcerous colitis and in all patients with Crohn's disease; of these, 93.5% had antibody titers of 1:32 and greater, while none of the patients with ulcerous colitis showed such titers. This study has led to the conclusion that the detection of these antibodies in high titers can be one of the criteria for the differential diagnosis of nonspecific ulcerous colitis and Crohn's disease.