Experimental study of measles immunity based on an index to neutrophil damage

Zakharova, T.R.; Titova, N.S.; Bolotovskiĭ, V.M.

Voprosy Virusologii 27(5): 88-90

1982


ISSN/ISBN: 0507-4088
PMID: 7147910
Document Number: 190812
Comparative studies for the elucidation of immunologic reactions in vaccination and infectious measles immunity were carried out. The delayed hypersensitivity was evaluated by the test of neutrophil alteration with the specific antigen according to V. N. Fradkin. The results indicate that the vaccine measles virus strain produces immunological alterations in animals accompanied by the development of sensitization to measles antigen. The observed alterations and changes in specific humoral immunity in experimental measles produced by a pathogenic virus are more manifest than those induced by the vaccine strain.

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