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Surface morphology of normal and virus-transformed cells in suspended state and their concanavalin a agglutinability

Samil'chuk, E.I.; Lapin, B.A.

Tsitologiia 24(7): 791-796

1982

ISSN/ISBN: 0041-3771
PMID: 6291200
Document Number: 190529
Suspended cells are heterogeneous in respect to their surface microrelief. The distribution of different microrelieves varies in different cultures. It depends on the mode of cell detachment from the substrate - by EDTA or trypsin. Oncogenic transformation is accompanied by both the increase and decrease of microvillous microrelief. There is no correlation between the surface morphology of transformed cells and their agglutinability by concanavalin A. The treatment with trypsin results in the increase of both agglutinability by concanavalin A and microvillious microrelief.

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