Ventricular volume characteristics and function in patients with single ventricle
Shimazaki, Y.
Nihon Kyobu Geka Gakkai 30(12): 1940-1951
1982
ISSN/ISBN: 0369-4739 PMID: 7169559 Document Number: 190274
Ventricular cavity volume measurements were performed in 20 patients with single ventricle with biplane cineangiocardiograms. There were 6 patients with a single left ventricle and 14 with a single right ventricle; atrioventricular valve regurgitation was evident in 6 of 14 patients with a common atrioventricular valve. Ventricular end-diastolic volume index ranged from 72-282ml/m2 with an average of 136 .+-. 51ml/m2 (SDM [SD of the mean]), and these ranged from 64-206 (115 .+-. 42%) of the sum of the normal left and right ventricular end-diastolic volumes. There was no significant difference in ventricular volume characteristics between patients with a single left and a single right ventricle. There was a high correlation of pulmonary to systemic flow ratios with end-diastolic volume index (r = 0.84, P < 0.001) or with end-diastolic volume/normal value (r = 0.66, P < 0.005). Therefore, the major factor affecting ventricular cavity volume in single ventricle is pulmonary flow which the ventricle ejects. Systemic to pulmonary arterial shunt should be effective to increase the ventricular cavity volume. Ejection fraction of single ventricle ranged from 0.40-0.64 (0.55 .+-. 0.06). There was no significant difference in ejection fraction between patients with a single left ventricle and a single right ventricle. The ejection fraction in patients with atrioventricular valve regurgitation averaged 0.49 .+-. 0.08, and it was significantly lower than the value (0.57 .+-. 0.04) in patients with atrioventricular incompetence (P < 0.01). Atrioventricular valve regurgitation might increase the ventricular cavity volume, although ventricular function became more depressed. The ventricular end-diastolic pressure of single ventricle ranged from 2-13 (8 .+-. 3) mmHg and did not correlate with end-diastolic volume. There was no significant difference in end-diastolic pressure between patients with a single left ventricle and a single right ventricle, and between patients with atrioventricular valve regurgitation and those without incompetence.