Genetic activity of 1,2-dichloroethylene. A) . in vitro studies
Galli, A.; Bauer, C.; Bronzetti, G.; Corsi, C.; Del Carratore, R.; Nieri, R.; Paolini, M.
Bollettino della Societa Italiana di Biologia Sperimentale 58(13): 860-863
1982
ISSN/ISBN: 0037-8771 PMID: 6751355 Document Number: 189334
1,2-dichloroethylene cis and trans were tested for their ability to induce point mutation, mitotic gene conversion and mitotic recombination in a diploid strain (D7) of the yeast Saccharomyces cerevisiae in a suspension test with and without a mammalian microsomal activation system. In this test 1,2-DCE cis and trans were toxic but not genetically active even with S9 activation.
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