Influence of septo-hippocampal pathway deafferentation on multiple forms of acetylcholinesterase in fascia dentata in the Rabbit
Karanova, M.V.; Budantsev, A.I.; Brazhnik, E.S.
Ukrainskii Biokhimicheskii Zhurnal 54(1): 82-85
1982
ISSN/ISBN: 0201-8470 PMID: 7058558 Document Number: 187468
Electrophoresis separation of membrane acetylcholinesterase in 5% PAAG resulted in five forms of the enzyme differing by electrophoretic mobility and velocity of ACh hydrolysis. The activity of isoforms (I, II) was decreased by 40 and 76, respectively, 4 days after deafferentiation of septo-hippocampal pathways. Changes in the activity were still greater 7 days after deafferentiation as compared with those mentioned above.