Molecular forms of acetylcholinesterase in the slow muscle and the fast muscle of the chicken
Koenig, J.; Vigny, M.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(6): 1069-1074
1978
ISSN/ISBN: 0037-9026 PMID: 159094 Document Number: 137501
Five molecular forms of AChE are present in the slow (ALD) and twitch (PLD) muscles of the chick. These forms have 4 S, 7 S, 11 S, 15 S and 20 S sedimentation coefficient in sucrose gradient. The heaviest forms, the 20 S and 15 S of AChE are absent in uninnervated muscles and present in innervated muscles. In innervated muscles, the 20 S and 15 S AChE are present in both nerve-free segments and end-plates zones. The 20 S and 15 S which are not specifically associated with the end-plate zones in the chick could be considered as a biochemical "marker" of neuromuscular interactions.