Plasma concentrations of chloramphenicol in birds

Clark, C.H.; Thomas, J.E.; Milton, J.L.; Goolsby, W.D.

American Journal of Veterinary Research 43(7): 1249-1253

1982


ISSN/ISBN: 0002-9645
PMID: 7103207
Document Number: 186839
The plasma concentrations of chloramphenicol . The biological half-lives of chloramphenicol ranged from 26 min in the pigeon, to 288.3 min in the bald eagle. In those birds studied, the oral route gave low and inconsistent plasma chloramphenicol concentrations. The i.m. route was the most satisfactory. Based on the data presented, and i.m. dose of 50 mg/kg would produce plasma concentrations above 1 .mu.g/ml for 8-12 h, except in the pigeon, macaw and conure.

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