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Effect of hyperbaric oxygenation on the oxidative phosphorylation in mitochondria of normal and ischemic myocardium

Reznikov, K.M.; Leonov, A.N.; Obolenskiĭ, A.L.

Voprosy Meditsinskoi Khimii 28(6): 24-27

1982

ISSN/ISBN: 0042-8809
PMID: 7157719
Document Number: 185277
Oxygen, under conditions of elevated pressure 303.975 kPi, was shown to alter oxidative phosphorylation in mitochondria of rabbit heart. Inhibition of oxidative phosphorylation in intact animals and stimulation--in rabbits with myocardial ischemia were observed under conditions of high oxygen pressure. With an increase in frequency of the hyperbaric oxygenation treatments the inhibitory effect if high pressure oxygen was strengthened.

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