Pneumonia in children with acute leukemia
Ochocka, M.; Ciepielewska, D.; Winnicki, S.
Materia Medica Polona. Polish Journal of Medicine and Pharmacy 14(1-2): 35-39
1982
ISSN/ISBN: 0025-5246 PMID: 7186993 Document Number: 184950
Analysis of 34 severe, interstitial cases of pneumonia in children in the course of acute leukemia (AL) is presented. Pneumonia developed in the period of an intensive chemo- and X-ray therapy already during hematologic remission. As etiologic factors, gram-negative bacteria were most commonly found, particularly Klebsiella pneumoniae. The possibility of a toxic and/or allergic reaction of the lung to treatment with cytostatics is discussed. Rapidly developing symptoms of circulatory and respiratory insufficiency with leukopenia below 1000/mm3 always indicated a bad prognosis. In 40% of cases pneumonia, despite intensive treatment, was a direct cause of death.
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