Periorbital ecchymoses as the initial sign in multiple myeloma
Loo, H.; Forman, W.B.; Levine, M.R.; Crum, E.D.; Rassiga, A.L.
Annals of Ophthalmology 14(11): 1066-1068
1982
ISSN/ISBN: 0003-4886 PMID: 7181338 Document Number: 183530
A 61-year-old man with bilateral recurrent periorbital ecchymoses was followed up for 36 months, at which time the diagnosis of multiple myeloma was established. However, in vitro tests of blood coagulation and platelet function gave normal findings. A biopsy specimen of the ecchymotic area showed no evidence of amyloid. Clinical and laboratory evaluation did not suggest another cause. The mechanism of the localized bleeding tendency could not be elucidated.