Activity and temperature dependence of acid peptidohydrolase in cerebral tissue of adrenalectomized rats under moderate hypothermia
Nurmagomedova, P.M.; Emirbekov, E.Z.
Ukrainskii Biokhimicheskii Zhurnal 53(5): 38-41
1981
ISSN/ISBN: 0201-8470 PMID: 7027562 Document Number: 182557
The activity of acid peptidehydrolase and its temperature dependence were determined in the cerebral cortex and totally in the midbrain and diencephalon of rats in normal state after a false operation and with bilateral adrenalectomy as well as under moderate (30.degree. C) hypothermia of intact, false-operated and adrenalectomized animals. The enzyme activity changed more significantly in the cerebral cortex. Adrenalectomy lowers it in the cortex at an incubation temperature of 30 and 20.degree. C. Incubation at a temperature of 37, 25, 20 and 15.degree. C decreases this activity under animal cooling as well. A combined effect of hypothermia and adrenalectomy on enzyme activity is not additive.