Change in cerebral bioelectric activity during whole body hypothermia and regional cooling of the head
Sumbatov, L.A.; Novoderezhkina, L.B.; Lekhtman, A.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 80(12): 14-17
1975
ISSN/ISBN: 0365-9615 PMID: 1225389 Document Number: 85080
Two series of experiments were conducted on dogs. In the first series of experiments dogs were subjected to deep hypothermia with an external chilling of the organism; in the second series-to the isolated deep hypothermia of the head with the maintenance of normothermia in the organism. Bioelectrical activity of the brain and circulation minute volume were recorded in the animals of both series. As revealed, depression of the bioelectrical activity was more pronounced and a prevalence of slow waves was observed in general hypothermia; at the same time a more even reduction of the electrical activity in all the EEG frequencies under study was seen in the series with local hypothermia. A reduction of the circulation minute volume was also more pronounced in the first series of experiments; in the authors' opinoin this was associated with the difference in the character of the EEG evolution with the same depth of hypothermia of the brain.