Effect of galascorbin on activity of lactate and malate dehydrogenases and their isoenzymic spectrum in experimental pyelonephritis
Chebotareva, V.D.; Petrun', N.M.; Burlaĭ, V.G.; Maidannik, V.G.
Ukrainskii Biokhimicheskii Zhurnal 53(4): 93-96
1981
ISSN/ISBN: 0201-8470 PMID: 7281262 Document Number: 182107
It is shown that per os administration of galascorbin to animals with acute experimental pyelonephritis in a dose of 100 mg/1 kg of mass per day normalizes the total activity of lactate dehydrogenase (EC 1.1.1.27), malate dehydrogenase (EC 1.1.1.37) and their isoenzymic spectrum in kidney tissue and blood serum. The content of pyruvic and lactic acids in blood serum also normalizes, that promotes a favourable course of the disease.