Suppressant effect of oxyfedrine on development of anaphylaxis in experimental animals
Poriadin, G.V.; Salmasi, Z.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 92(7): 72-74
1981
ISSN/ISBN: 0365-9615 PMID: 7295948 Document Number: 181605
Oxyfedrine (ildamen) which stimulates beta-adrenoreceptors of smooth muscles in concentrations increasing the tissue content of cAMP produced a dose-dependent inhibition of anaphylactic bronchospasm and contractions of the guinea-pig intestine induced by administration of ovalbumin. The results obtained provide evidence in favour of oxyfedrine use for suppression of immediate type allergic reactions with the involvement of smooth muscles.