Vincristine and prednisolone induction and reinforcement therapy for acute lymphoblastic leukaemia in children
Shetty, P.A.; Antia, P.K.; Jussawalla, D.J.
Indian Journal of Cancer 18(2): 150-152
1981
ISSN/ISBN: 0019-509X PMID: 6946958 Document Number: 180439
The treatment of ALL goes on conventional lines of (1) induction, (2) cranial prophylaxis and (3) maintenance. Children (25) between age 3-14 yr were treated uniformly for induction and CNS prophylaxis. During the maintenance phase 18 children in remission were randomized into 2 arms of a controlled study investigating the role of vincristine and prednisolone in induction therapy, and the importance of these drugs in reinforcement therapy to maintain long-term remission.