Top Abstract Purchase Related
Home
>
Node
>
Subnode

Determination of lactic dehydrogenase isoenzymes in precancerous and cancerous gastric mucosa

Mazzarino, C.; Malaponte, G.; Travali, S.; Sanfilippo, G.; Russo, A.

Bollettino della Societa Italiana di Biologia Sperimentale 57(19): 2004-2010

1981

ISSN/ISBN: 0037-8771
PMID: 7317193
Document Number: 180016
We have studied modifications of LDH isoenzymes pattern in normal human gastric mucosa as well as in adenocarcinoma and precancerous lesions of the stomac (gastritis and ulcer); samples from the injured and the surrounding non-injured area were examined, drawing up the isoenzymes, using Tris-buffer pH 7,4 at 4 degrees C and performing the determination within 1 h - because of the high chronolability of the fractions LDH and LDH by cellogol electrophoresis separation. We have always noticed - especially in samples from adenocarcinoma- a shifting toward the M chains, with a clear increase of the fractions LDH4 and LDH5; this has been noticed even in the surrounding non-injured area.

Document emailed within 1 workday
Secure & encrypted payments

Xu, J.J. 1984: Value of tissue lactic dehydrogenase (LDH) and its isoenzymes in the diagnosis of carcinoma of the esophagus and gastric cardia Zhonghua Zhong Liu Za Zhi 6(4): 273-277
Wang, Z.S. 1985: Activity of lactic dehydrogenase and its isoenzyme in intestinal metaplasia of the gastric mucosa, early and advanced gastric carcinoma Zhonghua Zhong Liu Za Zhi 7(4): 260-262
Angelini, C.; Cazzato, G.; Fardin, P. 1970: Behavior of serum isoenzymes of lactic dehydrogenase in various muscular diseases Acta Neurologica 25(6): 633-654
Sobel, B.E.; Henry, P.D.; Ehrlich, B.J.; Bloor, C.M. 1970: Altered myocardial lactic dehydrogenase isoenzymes in experimental cardiac hypertrophy Laboratory Investigation; a Journal of Technical Methods and Pathology 22(1): 23-27
Vrba, M.; Kamarýt, J. 1971: Lactic dehydrogenase (LDH) isoenzymes in cell cultures from different human tissues and organs Folia Biologica 17(2): 128-133
Borgard, J.P.; Goguelin, A.; Pesnel, G.; Legrand, P.; Squinazi, F.; Fabre, A.; Reinert, P.; Canet, J.; Geslin, P.; Doussin, A. 1982: Cerebrospinal fluid lactic dehydrogenase and its isoenzymes analysis in meningitis. Evaluation of 10 years Archives Francaises de Pediatrie 39(5): 295-301
Seck, I.; Wane, A.B.; Desmet, G. 1970: Serum lactic dehydrogenase and its isoenzymes: technic of study and results in adult Africans in Dakar Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 164(8): 1900-1905
Kapellerová, A.; Sulko, M.; Klacanský, I. 1977: Activity of lactic acid dehydrogenase and its isoenzymes in nasopharyngeal and tracheobronchial secretion of 12- to 24-month-old babies with acute diseases of the respiratory organs Bratislavske Lekarske Listy 67(5): 592-596
Saravanan, C.S.; Govindarajulu, P.; Rao, R.N. 1979: Lactate dehydrogenase and its isoenzymes in gastric cancer Indian Journal of Cancer 16(1): 42-44
Tsygankov, A.P.; Bandurko, L.N.; Tsodikova, L.B. 1970: Histochemical determination of lactate dehydrogenase isoenzymes Arkhiv Patologii 33(2): 73-76
Poddubnyĭ, B.K.; Nechipaĭ, A.M.; Kuvshinov, I.P.; Rottenberg, V.I.; Chistiakova, O.V. 1987: Dysplasia as a precancerous condition of the epithelium of the gastric mucosa Sovetskaia Meditsina 8: 66-69
Plomteux, G. 1970: Comparison of 2 technics for the determination of multimolecular forms of lactic dehydrogenase Annales de Biologie Clinique 28(2): 131-135
Ignatowska-Switalska, H.; Wasińska, H. 1976: Diagnostic value of lactic dehydrogenase determination in pulmonary artery embolism Kardiologia Polska 19(2): 109-114
Wang, R. 1989: Pathologic comparison between gastric carcinoma and lesions in peri-cancerous mucosa from two districts with different mortality rates in Gansu Province Zhonghua Zhong Liu Za Zhi 11(3): 187-190
Madiwale, M.S.; Mahal, H.S.; Master, R.W. 1972: Isoenzymes of lactate and malate dehydrogenase in the blood as an aid in species determination in forensic examinations Archiv für Kriminologie 150(3): 112-117
Volkova, L.D. 1974: Clinical value of the determination of isoenzymes of malate and lactate dehydrogenase in the urine in chronic kidney diseases in children Pediatriia 10: 71-73
Yang, Z.; Wang, C.; Chen, J.; Wang, H.; Wang, Y.; Ma, F. 2015: Effects of moxibustion on cell proliferative factors in gastric mucosa in rats with precancerous lesions of chronic atrophic gastritis Zhongguo Zhen Jiu 35(12): 1269-1273
Sakurai, Y.; Furuta, S.; Sunagawa, R.; Tonomura, S.; Inaba, K.; Shoji, M.; Nakamura, Y.; Isogaki, J.; Komori, Y.; Uyama, I.; Kamoshida, S.; Tsutsumi, Y. 2007: Orotate phosphoribosyltransferase levels in gastric carcinoma and normal gastric mucosa - correlation with thymidylate synthase and dihydropyrimidine dehydrogenase levels and the changes after neoadjuvant chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 34(10): 1581-1587
Zubikova, I.I.; Bokovoĭ, A.G.; Vaganov, P.D.; Uryvchikov, G.A.; Trakhtengerts, M.I. 1976: Isoenzymes of lactate dehydrogenase and malate dehydrogenase in blood in several diseases complicated by liver lesions Pediatriia 3: 63-64
Haworth, J.C.; Perry, T.L.; Blass, J.P.; Hansen, S.; Urquhart, N. 1976: Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes Pediatrics 58(4): 564-572