Lipid levels in hemodialyzed diabetic uremic patients
Carvounis, C.P.; Feinfeld, D.A.; Weinstein, E.; Lipner, H.I.; Sadigali, R.; Avram, M.M.
New York State Journal of Medicine 81(7): 1053-1056
1981
ISSN/ISBN: 0028-7628 PMID: 6942246 Document Number: 179810
Levels of triglycerides, cholesterol, plasma insulin, TSH (thyrotropin) and GH (growth hormone) were asured in diabetic and nondiabetic patients on hemodialysis. Diabetics not requiring insulin had significantly lower levels of cholesterol and triglycerides than controls; in diabetics taking insulin, these differences were not significant. There was an inverse relationship between plasma insulin levels and plasma triglyceride levels in the diabetics not taking insulin, whereas the normal direct relationship between these 2 variables was found in controls. A direct relationship between plasma TSH and GH was found in uremic controls; an inverse relationship between these 2 hormones was found in diabetics not requiring insulin. This perturbation may have an effect on lipid levels. Hyperlipidemia may not be important in the pathogenesis of arteriosclerosis in diabetics on chronic hemodialysis.