Serum lipids in acute myocardial infarction
Giachetti, M.; Denegri, E.; Pedroni, P.; Valtolina, M.
Quaderni Sclavo di Diagnostica Clinica E di Laboratorio 17(4): 495-504
1981
ISSN/ISBN: 0033-4979 PMID: 7347829 Document Number: 179743
The following lipidic fractions were determined in a population of patients with acute myocardial infarction (AMI) and in a control group: total cholesterol, triglycerides, total phospholipids, HDL-cholesterol and HDL-phospholipids. The assays were repeated four times during the hospitalization of the patients admitted for AMI. With respect to total cholesterol, triglycerides and HDL-cholesterol, our findings correlated well with the results published in literature, inasmuch as they confirmed positive interrelation for total cholesterol/AMI and triglycerides/AMI ratios and a negative interrelation for HDL-cholesterol/AMI ratio. During the 20 days following infarction, these three parameters decreased to significantly lower values. The relationship linking total phospholipids and HDL-phospholipids to myocardial infarction has not yet been sufficiently investigated and the few available seem rather contradictory. The results which we have obtained seem to indicate a connection between increased total phospholipids and AMI, whereas HDL-phospholipids do not seem to provide any discriminant indication.