A disseminated form of Histoplasma duboisii histoplasmosis in a Zaïre patient
Lamey, B.
Medecine Tropicale Revue du Corps de Sante Colonial 41(6): 661-663
1981
ISSN/ISBN: 0025-682X PMID: 6280015 Document Number: 178672
Report of a case of histoplasmosis observed in Zaïre with lymphatic, pulmonary and intestinal localizations. Histoplasma duboisii was abundant in the stools, sputum and lymphatic tissue. With no amphotericine B available, treatment first started with high dosage of miconazole which had no effect. Ketoconazole have been, then, tried, giving a clinical and biological improvement, but patient still in a very bad condition, died. Ketoconazole seems to have a rapid but not lasting effect, even with increased dosages.