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Reliability of three screening tests in detection of glucose-6-phosphate dehydrogenase deficiency in adults and neonates

Sood, S.K.; Madan, N.; Talwar, N.; Maheshwari, A.; Jayant, D.; Bhargava, S.K.

Indian Journal of Pathology and Microbiology 24(2): 89-99

1981

ISSN/ISBN: 0377-4929
PMID: 7287108
Document Number: 178251
2128 Specimens of blood from adult subjects and non-jaundiced and hyperbilirubinaemic neonates of both sexes were screened for G6PD . The deficiency was confirmed by the quantitative spectrophotometric assay of Glock and McLean. Comparison of the results of the 3 screening tests showed that they are equally sensitive and reliable in detecting G6PD deficiency. MRT is recommended as the method of choice because it is sensitive, simple and inexpensive. FST is specific, sensitive and is especially suitable for mass screening.

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