The influence of splenic tissue implantation upon platelet population in rabbits after splenectomy
Smidt, N.; Laufer, N.; Grover, N.B.; Freund, H.R.; Charuzi, I.
Surgery Gynecology and Obstetrics 153(5): 717-720
1981
ISSN/ISBN: 0039-6087 PMID: 7292272 Document Number: 176790
An investigation of the behavior of the blood platelet population following splenectomy and autologous splenic tissue implantation has been done on the rabbit. A bimodal rise in platelet size and count is observed in the postoperative period. After splenectomy, a 722 per cent increase in the platelet count and a 21.9 percent rise in the platelet size are found. These increases are abolished by the implantation of splenic tissue. The existence of a splenic humoral factor that controls platelet production in the bone marrow is possible.