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Ovine histocompatibility complex OLA and enzymatic markers in hamster X sheep hybrids. I. Asynteny between PGM3-ME1 and OLA

Millot, P.; Saidi-Mehtar, N.; Hors-Cayla, M.C.

Annales de Genetique 24(2): 82-88

1981

ISSN/ISBN: 0003-3995
PMID: 6460463
Document Number: 176695
Eighteen independent hamster X sheep fibroblast hybrids have been obtained. OLA typing of parental cells has shown that ovine fibroblasts carry the OLA A1, A8, B7, and B9 specificities. Analysis of the segregation of the OLA genes compared with the segregation of the 16 enzymatic markers studied previously indicated that, in contrast to the situation and man and certain other mammals, the genes of the histocompatibility complex of ovines (OLA) and those coding for the enzymes PGM3 and and ME1 are asyntenic. No synteny between OLA and any other enzymatic marker studied has been established.

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