Primary systemic amyloidosis-a variant of plasma cell dyscrasia
Kueh, Y.K.; Fong, P.H.; Ee, B.K.; Teoh, P.C.
Singapore Medical Journal 22(4): 207-209
1981
ISSN/ISBN: 0037-5675 PMID: 7323827 Document Number: 176529
A case of primary systemic amyloidosis with features of plasma cell dyscrasia is presented. The patient had macroglossia and bilateral carpal tunnel syndrome. The diagnosis was confirmed by tongue and rectal biopsies. Increased bone marrow plasma cells and the presence of urinary .kappa. light chains were present. Serum immunoelectrophoresis and skeletal survey were normal. Primary systemic amyloidosis lies within the spectrum of plasma cell disorder is supported by its association with features of plasma cell disease without overt myelomatosis and by the immunochemical similarity of its fibril to that of myeloma amyloid.