Role of the immunoglobulin coat in the process of microorganism phagocytosis
Bykov, A.S.; Lazurenko, I.S.; Seleznev, A.S.
Arkhiv Patologii 43(9): 10-16
1981
ISSN/ISBN: 0004-1955 PMID: 7305673 Document Number: 172209
Comparative electron microscopic examinations of staphylococcus aureus under different conditions (in a pulmonary abscess of a patient, in a short-time contact with serum and blood cells of a donor, and experimental infection of white mice) revealed dissimilar possibilities of formation of an immunoglobulin coat on the surface of bacterial cell wall. Upon a short-time contact of S. aureus with human blood serum in vitro an immunoglobulin coating appeared on the bacterial cell wall. In control experiments with staphylococci killed with glutaraldehyde and treated with methycilline the possibility of formation of microcapsule by staphylococci was excluded. No immunoglobulin coating was detected in a protracted suppurative process. In the pulmonary abscess, different gram-positive and gram-negative bacteria were found.