Tissue sources and clinical application of four enzymes in phocid seals
Austin, T.; Geraci, J.R.
American Journal of Veterinary Research 42(5): 834-837
1981
ISSN/ISBN: 0002-9645 PMID: 6114694 Document Number: 172208
Tissue distribution and plasma activity values of creatine kinase (CK), aldolase (ALS), gamma -glutamyltransferase (GGT), and leucine aminopeptidase (LAP) were determined in six ringed seals, Phoca hispida, and in seven harp seals, P. groenlandica. Muscle tissues had the highest activity of CK and ALS, though high activity of ALS was also in most other tissues. The LAP and GGT were mostly concentrated in the kidneys; tissue LAP activity was generally low. Reference plasma values were determined in 17 ringed and 15 harp seals. The CK and GGT, respectively, are recommended for monitoring exertional stress and hepatobiliary dysfunction in phocid seals.