Oxytropium bromide in bronchial asthma: comparison of metered dose inhaler and powder inhalation of the anticholinergic bronchodilator oxytropium bromide in protection against acetylcholine and histamine provocation
Beumer, H.M.; Grieben, C.; Schuijt, C.; Siebelink, J.
International Journal of Clinical Pharmacology Therapy and Toxicology 19(4): 168-170
1981
ISSN/ISBN: 0174-4879 PMID: 7263104 Document Number: 171410
A marked protective effect of 0.2 mg oxitropium bromide (Ba 253), administered by inhalation, was observed against experimental provocation with a 3% acetylcholine solution . There is no difference between application by a metered dose inhaler or by powder inhalation. There is no marked protective effect of 0.2 mg oxitropium bromide administered by inhalation (aerosol or powder) against experimental provocation with a 0.3% histamine solution.