The effect of tiofedrine on brain perfusion in patients with cerebrovascular insufficiency
Ott, E.; Lechner, H.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 36(4): 124-126
1981
ISSN/ISBN: 0044-2542 PMID: 7222859 Document Number: 169016
The influence of intravenous tinofedrine (0.12 to 0.17 mg/kg body-weight) on cerebral blood flow has been investigated in 23 patients (mean age 65 years) with subacute cerebral infarction. The mean cerebral blood flow increased significantly by 20% in the infarcted hemisphere during a treatment period of 12 days. Clinically an improvement of an initially depressed vigilance level was established which was quantified psychopathometrically in 4 patients.
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