Viral particles in the hepatocytes of Rana esculenta (L)
Mişcalencu, D.; Alfy, M.E.; Mailat, F.; Mihăescu, G.
Virologie 32(2): 123-125
1981
ISSN/ISBN: 0253-181X PMID: 6972664 Document Number: 168947
The hepatocytes of R. esculenta exhibit hexagonal (probably icosahedral) viral particles disseminated in the cytoplasm among cellular organelles (mitochondria, cisternae of the endoplasmic reticulum and Golgi complex). The particles consist of an electron-dense core (nucleoid) and a less electron-dense envelope (capsid). Empty capsids (without nucleoid) or semilunar capsid fragments can sometimes be observed. The virus seems to be cytoplasmic, as it has not been found in the nucleus of hepatocytes.