Dopamine regulation of testicular activity in intact and hypophysectomized frogs, Rana esculenta
Minucci, S.; Fasano, S.; D'Antonio, M.; Pierantoni, R.
Experientia 49(1): 65-67
1993
ISSN/ISBN: 0014-4754 PMID: 8428613 Document Number: 407835
In intact frogs, both GnRHA and L-dopa were able to increase testicular and plasma androgen levels and to induce spermiation. The dopamine antagonist pimozide inhibited both the effects of L-dopa but not those of GnRHa. Hypophysectomy reduced androgen levels, but spermiation was still induced by both GnRHa and L-dopa, suggesting that these agents can directly influence the testis through a route not involving the pars distalis. Again, pimozide antagonised spermiation induced by L-dopa but not that induced by GnRHa.