Effect of hydrochlorothiazide and furosemide on the overall calcium content in aortal tissue of rats
Kovalcík, V.; Drábková, E.
Bratislavske Lekarske Listy 75(1): 24-28
1981
ISSN/ISBN: 0006-9248 PMID: 7214167 Document Number: 168624
Within the 24 h period following peroral administration of hydrochlorothiazide to rats in doses of 125 mg/kg of body wt, a statistically significant dose-dependent decrease of the total Ca content was determined in the aortal tissue. I.p. administration of furosemide in doses of 50 mg/kg and 100 mg/kg of body wt failed to affect the content of Ca in the aortal tissue within the 2 h period under study.
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